Why do some people age faster than others? We’ve all seen people – high school reunions come to mind – who have the same chronological age, but different biological ages: with the same “age”, one person looks ten years older (or younger) than another. If aging is related to cell senescence and cell senescence depends […]
3Most of us – when we think of cells at all – seldom appreciate that the idea of a “cell” is a modern idea, not quite two centuries old. One of the tenets of cell theory is that cells are the “basic unit of life”. This makes some sense but note that while the components […]
0For those interested in knowing where this blog is going (or where it has been), here is an index of all previous and planned posts for this series on Aging and Disease. Note that the planned posts may change as we progress. 0.1 Prologue 1.0 Aging, our purpose, our perspective 1.1 Aging, what is isn’t […]
0Misconceptions regarding the current model of aging are rampant and they tend to fall into one of several categories. These include Straw man arguments, unfamiliarity with how age-related human pathology occurs, simplistic views cell senescence, genes, and expression, or misguided approaches to measuring telomeres (usually in the wrong cells). The Earth can’t possibly be round, […]
1How does aging work? So far, in the prologue (section 0) and the section 1 posts, we have discussed a perspective, what aging isn’t (and is), and what we need to explain in any accurate model of aging. In this post, I provide an overview of how the aging process occurs, from cell division to […]
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